Equivalency Table

Drug

Oral/Rectal Route

Parenteral Route

Conversion Ratio to 
Oral Morphine

Equianalgesic Dose of Oral Morphine

Morphine sulfate 30mg Oral morphine 10mg of parenteral morphine Parenteral morphine is 3 times as potent as oral morphine 30mg Oral morphine
Oxycodone 20mg of oral oxycodone NA Oral Oxycodone is roughly 1.5 times more potent than oral morphine 30mg Oral morphine
Hydrocodone 20mg of oral hydrocodone NA Oral hydrocodone is roughly 1.5 times more potent than oral morphine 30mg Oral morphine
Hydromorphone 7mg of oral hydromorphone 1.5mg of parenteral hydromorphone Oral hydromorphone is about 4-7 times as potent as oral morphine

Parenteral hydromorphone is 20 times as potent as oral morphine

30mg Oral morphine
Fentanyl NA 15 micrograms/hr Transdermal fentanyl isapproximately 80 times as potent as morphine

(This is based on studies converting from Morphine to fentanyl. Currently, there are no empirical studies converting fentanyl to morphine).

30mg Oral morphine
Meperidine

Meperidine is nota recommended drug in a palliative care setting and is to be avoided.

If a patient with chronic pain is on meperidine, convert patient to an equianalgesic dose of one of the other opioids listed in this table.

300mg of oral meperidine 75mg of parenteral meperidine Oral Morphine is about 10 timesmore potent than oral meperidine and about twice more potent as parenteral meperidine (mg for mg) 30mg Oral morphine

 

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